Clear all User Presets and set to Factory Default Configuration.
1. Press and hold the Setup button until it blinks 2 times, then release and press 980. The power button should now blink 4 times.
2. Press and hold the Setup button until it blinks 2 times, then release and press 977. The power button should now blink 4 times.
3. Test the remote operation. If no response, proceed to #4.
4. Repeat step 2 and test. This may take up to 4 times.
Unless you have a Samsung TV, you will need to set up the remote to control your TV again.